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1

The solubility of α-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease

Bruce C. V. Campbell, Catriona A. McLean, Janetta G. Culvenor, Wei Ping Gai, Peter C. Blumbergs, Pekka Jäkälä, Konrad Beyreuther, Colin L. Masters, Qiao-Xin Li

Journal:

Journal of Neurochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 773 KB

english, 2001

2

Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways

Anthony R. White, Xudong Huang, Michael F. Jobling, Colin J. Barrow, Konrad Beyreuther, Colin L. Masters, Ashley I. Bush, Roberto Cappai

Journal:

Journal of Neurochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 828 KB

english, 2001

3

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Kang, Jie, Lemaire, Hans-Georg, Unterbeck, Axel, Salbaum, J. Michael, Masters, Colin L., Grzeschik, Karl-Heinz, Multhaup, Gerd, Beyreuther, Konrad, Müller-Hill, Benno

Journal:

Année:

1987

Fichier:

PDF, 466 KB

1987

4

Cholesterol Depletion Inhibits the Generation of β -amyloid in Hippocampal Neurons

Mikael Simons, Patrick Keller, Bart De Strooper, Konrad Beyreuther, Carlos G. Dotti and Kai Simons

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1998

5

A presenilin 1 mutation in the first case of Alzheimer's disease: Revisited

Rupp, Carsten, Beyreuther, Konrad, Maurer, Konrad, Kins, Stefan

Journal:

Alzheimer's & Dementia

Année:

2014

Langue:

english

Fichier:

PDF, 557 KB

english, 2014

6

Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment

Janetta G. Culvenor, Fran Maher, Geneviève Evin, Fiorella Malchiodi-Albedi, Roberto Cappai, John R. Underwood, John B. Davis, Eric H. Karran, Gareth W. Roberts, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Neuroscience Research

Année:

1997

Langue:

english

Fichier:

PDF, 395 KB

english, 1997

7

Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies

Anke Diehlmann, Nobuo Ida, Sascha Weggen, Jürgen Grünberg, Christian Haass, Colin L. Masters, Thomas A. Bayer, Konrad Beyreuther

Journal:

Journal of Neuroscience Research

Année:

1999

Langue:

english

Fichier:

PDF, 707 KB

english, 1999

8

Aβ peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture

Su San Mok, Andrew B. Clippingdale, Konrad Beyreuther, Colin L. Masters, Colin J. Barrow, David H. Small

Journal:

Journal of Neuroscience Research

Année:

2000

Langue:

english

Fichier:

PDF, 156 KB

english, 2000

9

Cerebrospinal fluid Aβ42 is increased early in sporadic Alzheimer's disease and declines with disease progression

Malene Jensen, Johannes Schröder, Mari Blomberg, Benita Engvall, Johannes Pantel, Nobuo Ida, Hans Basun, Lars-Olof Wahlund, Egon Werle, Marek Jauss, Konrad Beyreuther, Lars Lannfelt, Tobias Hartmann

Journal:

Annals of Neurology

Année:

1999

Langue:

english

Fichier:

PDF, 234 KB

english, 1999

10

Novel Leu723Pro amyloid precursor protein mutation increases amyloid β42(43) peptide levels and induces apoptosis

John B. J. Kwok, Qiao-Xin Li, Marianne Hallupp, Scott Whyte, David Ames, Konrad Beyreuther, Colin L. Masters, Peter R. Schofield

Journal:

Annals of Neurology

Année:

2000

Langue:

english

Fichier:

PDF, 3.23 MB

english, 2000

11

Increased expression of the amyloid precursor β-secretase in Alzheimer's disease

R. M. Damian Holsinger, Catriona A. McLean, Konrad Beyreuther, Colin L. Masters, Geneviève Evin

Journal:

Annals of Neurology

Année:

2002

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2002

12

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

Mikael Simons, Frank Schwärzler, Dieter Lütjohann, Klaus Von Bergmann, Konrad Beyreuther, Johannes Dichgans, Henning Wormstall, Tobias Hartmann, Jörg B. Schulz

Journal:

Annals of Neurology

Année:

2002

Langue:

english

Fichier:

PDF, 89 KB

english, 2002

13

An abnormality of plasma amyloid protein precursor in Alzheimer's disease

Ashley I. Bush, Scott Whyte, Linda D. Thomas, Timothy G. Williamson, Cees J. Van Tiggelen, Jon Currie, David H. Small, Robert D. Moir, Qiao-Xin Li, Baden Rumble, Ursula Mönning, Konrad Beyreuther, Dr.

Journal:

Annals of Neurology

Année:

1992

Langue:

english

Fichier:

PDF, 938 KB

english, 1992

14

Missense mutations of the PS-1/S182 gene in german early-onset Alzheimer's disease patients

Rupert Sandbrink, Dai Zhang, Konrad Beyreuther, Sibylle Schaeffer, Joachim Bauer, Colin L. Masters, Hans Förstl

Journal:

Annals of Neurology

Année:

1996

Langue:

english

Fichier:

PDF, 231 KB

english, 1996

15

Collection and normal levels of the amyloid precursor protein in plasma

Scott Whyte, Neil Wilson, Jon Currie, Paul Maruff, Valencia Malone, Ruxsana Shafiq -Antonacci, Peter Tyler, Kathryn L. Derry, John Underwood, Qiao-Xin Li, Konrad Beyreuther, Dr Colin L. Masters

Journal:

Annals of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 392 KB

english, 1997

16

ChemInform Abstract: Synthesis of Antioxidative and Antiinflammatory Drugs Glucoconjugates.

Rainer K. Uhrig, Martin A. Picard, Konrad Beyreuther, Manfred Wiessler

Journal:

Année:

2000

Fichier:

PDF, 32 KB

2000

17

Myeloma class switch variant X63.2aRI-16 secretes IgG2a and IgG1 with identical VDJ sequence

Siegfried Zaiss, Konrad Beyreuther

Journal:

European Journal of Immunology

Année:

1983

Langue:

english

Fichier:

PDF, 605 KB

english, 1983

18

Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126

Leanne R. Stewart, Anthony R. White, Michael F. Jobling, B. Elise Needham, Fran Maher, James Thyer, Konrad Beyreuther, Colin L. Masters, Steven J. Collins, Roberto Cappai

Journal:

Journal of Neuroscience Research

Année:

2001

Langue:

english

Fichier:

PDF, 319 KB

english, 2001

19

β-amyloid precursor protein can be transported independent of any sorting signal to the axonal and dendritic compartment

Simone Back, Petra Haas, Jakob-A. Tschäpe, Tomas Gruebl, Joachim Kirsch, Ulrike Müller, Konrad Beyreuther, Stefan Kins

Journal:

Journal of Neuroscience Research

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

20

Synthesis of antioxidative and anti-inflammatory drugs glucoconjugates

Rainer K. Uhrig, Martin A. Picard, Konrad Beyreuther, Manfred Wiessler

Journal:

Carbohydrate Research

Année:

2000

Langue:

english

Fichier:

PDF, 162 KB

english, 2000

21

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase

Janelle Nunan, Mark S. Shearman, Frédéric Checler, Roberto Cappai, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 602 KB

english, 2001

22

Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein

Anna Henry, Qiao-Xin LI, Denise Galatis, Lars Hesse, Gerd Multhaup, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

British Journal of Haematology

Année:

1998

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1998

23

Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine

Su San Mok, Bradley J. Turner, Konrad Beyreuther, Colin L. Masters, Colin J. Barrow, David H. Small

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 254 KB

english, 2002

24

Selecting cells with different Alzheimer's disease γ-secretase activity using FACS : Differential effect of presenilin exon 9 deletion on γ- and ε-cleavage

M. Fleur Sernee, Geneviève Evin, Janetta G. Culvenor, José A. Villadangos, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 325 KB

english, 2003

25

The amyloid β-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons

Mark D. Caswell, Su San Mok, Anna Henry, Roberto Cappai, Genevieve Klug, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 483 KB

english, 1999

26

Amyloid precursor protein of Alzheimer’s disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures

Elsdon Storey, Melissa Katz, Yardenah Brickman, Konrad Beyreuther, Colin. L. Masters

Journal:

European Journal of Neuroscience

Année:

1999

Langue:

english

Fichier:

PDF, 429 KB

english, 1999

27

Affinity Purification of Proteoglycans that Bind to the Amyloid Protein Precursor of Alzheimer's Disease

Timothy G. Williamson, Victor Nurcombe, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 914 KB

english, 1995

28

Identification of Heparin-Binding Domains in the Amyloid Precursor Protein of Alzheimer's Disease by Deletion Mutagenesis and Peptide Mapping

Heidi J. Clarris, Roberto Cappai, Damien Heffernan, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1997

29

The Amyloid β-Protein of Alzheimer's Disease Increases Acetylcholinesterase Expression by Increasing Intracellular Calcium in Embryonal Carcinoma P19 Cells

Gian Sberna, Javier Sáez-Valero, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Journal of Neurochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 839 KB

english, 1997

30

Acetylcholinesterase Is Increased in the Brains of Transgenic Mice Expressing the C-Terminal Fragment (CT100) of the β-Amyloid Protein Precursor of Alzheimer's Disease

Gian Sberna, Javier Sáez-Valero, Qiao-Xin Li, Christian Czech, Konrad Beyreuther, Colin L. Masters, Catriona A. McLean, David H. Small

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 861 KB

english, 1998

31

Exacerbation of Copper Toxicity in Primary Neuronal Cultures Depleted of Cellular Glutathione

Anthony R. White, Ashley I. Bush, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 774 KB

english, 1999

32

The Hydrophobic Core Sequence Modulates the Neurotoxic and Secondary Structure Properties of the Prion Peptide 106-126

Michael F. Jobling, Leanne R. Stewart, Anthony R. White, Catriona McLean, Anna Friedhuber, Fran Maher, Konrad Beyreuther, Colin L. Masters, Colin J. Barrow, Steven J. Collins, Roberto Cappai

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 266 KB

english, 1999

33

Novel Effects of FCCP [Carbonyl Cyanide p-(Trifluoromethoxy)phenylhydrazone] on Amyloid Precursor Protein Processing

Bruce P. Connop, Robert L. Thies, Konrad Beyreuther, Nobuo Ida, Peter B. Reiner

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 242 KB

english, 1999

34

Proteolytic Fragments of Alzheimer’s Disease-Associated Presenilin 1 Are Present in Synaptic Organelles and Growth Cone Membranes of Rat Brain

Dirk Beher, Christine Elle, John Underwood, John B. Davis, Robin Ward, Eric Karran, Colin L. Masters, Konrad Beyreuther, Gerd Multhaup

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 284 KB

english, 1999

35

Substrate-Bound β-Amyloid Peptides Inhibit Cell Adhesion and Neurite Outgrowth in Primary Neuronal Cultures

Ronald B. Postuma, Weilan He, Janelle Nunan, Konrad Beyreuther, Colin L. Masters, Colin J. Barrow, David H. Small

Journal:

Journal of Neurochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 261 KB

english, 2000

36

Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition

Lisa R. Fodero, Javier Sáez-Valero, Catriona A. McLean, Ralph N. Martins, Konrad Beyreuther, Colin L. Masters, , David H. Small

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 401 KB

english, 2002

37

A synthetic substrate assay for the gamma-secretase of the β-A4 amyloid of alzheimer's disease

Dr. Geneviève Evin, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Peptide Science

Année:

1995

Langue:

english

Fichier:

PDF, 600 KB

english, 1995

38

Recognition of two initiation codons for the synthesis of phage fd gene 2 protein

Thomas F. Meyer, Konrad Beyreuther, Klaus Geider

Journal:

Molecular Genetics and Genomics

Année:

1980

Langue:

english

Fichier:

PDF, 537 KB

english, 1980

39

N-terminal sequence of phage lambda repressor

Konrad Beyreuther, Bruno Gronenborn

Journal:

Molecular Genetics and Genomics

Année:

1976

Langue:

english

Fichier:

PDF, 264 KB

english, 1976

40

A structural somatic variant of the Kkantigen is generated by point mutation

Günther Karmann, Konrad T. Beyreuther, Matthias Cramer, Bodo Holtkamp, Susanne Proksa, Klaus Rajewsky

Journal:

Année:

1985

Langue:

english

Fichier:

PDF, 810 KB

english, 1985

41

Specific binding of the alzheimer βA4 amyloid precursor to collagen, laminin, and heparin

Gerd Multhaup, Ashley I. Bush, Peter Pollwein, Colin L. Masters, Konrad Beyreuther

Journal:

The Protein Journal

Année:

1992

Langue:

english

Fichier:

PDF, 239 KB

english, 1992

42

Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer’s disease

Thomas A. Bayer, Krzysztof Paliga, Sascha Weggen, O. D. Wiestler, Konrad Beyreuther, Gerd Multhaup

Journal:

Acta Neuropathologica

Année:

1997

Langue:

english

Fichier:

PDF, 399 KB

english, 1997

43

Reverse relationship between β-amyloid precursor protein and β-amyloid peptide plaques in Down’s syndrome versus sporadic/familial Alzheimer’s disease

Rupert Egensperger, Sascha Weggen, Nobua Ida, Gerd Multhaup, Ralf Schnabel, Konrad Beyreuther, T. A. Bayer

Journal:

Acta Neuropathologica

Année:

1999

Langue:

english

Fichier:

PDF, 260 KB

english, 1999

44

Iron inhibits neurotoxicity induced by trace copper and biological reductants

AnthonyR. White, KevinJ. Barnham, Xudong Huang, Irene Voltakis, Konrad Beyreuther, ColinL. Masters, RobertA. Cherny, AshleyI. Bush, Roberto Cappai

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 417 KB

english, 2004

45

Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity

Patricia Rusu, Anna Jansen, Peter Soba, Joachim Kirsch, Alexander Löwer, Gunter Merdes, Yung-Hui Kuan, Anita Jung, Konrad Beyreuther, Ole Kjaerulff, Stefan Kins

Journal:

European Journal of Neuroscience

Année:

2007

Langue:

english

Fichier:

PDF, 937 KB

english, 2007

46

Human Brain βA4 Amyloid Protein Precursor of Alzheimer's Disease: Purification and Partial Characterization

Robert D. Moir, Ralph N. Martins, Ashley I. Bush, David H. Small, Elizabeth A. Milward, Baden A. Rumble, Gerd Multhaup, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Neurochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1992

47

Clues to the Etiology of Alzheimer's Disease Through the Study of the Amyloid Precursor Protein

Colin L. Masters, Konrad Beyreuther

Journal:

Brain Pathology

Année:

1997

Langue:

english

Fichier:

PDF, 54 KB

english, 1997

48

Intraneuronal APP/Aβ Trafficking and Plaque Formation in β-Amyloid Precursor Protein and Presenilin-1 Transgenic Mice

Oliver Wirths, Gerd Multhaup, Christian Czech, Nicole Feldmann, Véronique Blanchard, Günter Tremp, Konrad Beyreuther, Laurent Pradier, Thomas A. Bayer

Journal:

Brain Pathology

Année:

2002

Langue:

english

Fichier:

PDF, 737 KB

english, 2002

49

Key Factors in Alzheimer's Disease: β-amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

Thomas A. Bayer, Oliver Wirths, Katalin Majtényi, Tobias Hartmann, Gerd Multhaup, Konrad Beyreuther, Christian Czech

Journal:

Brain Pathology

Année:

2001

Langue:

english

Fichier:

PDF, 236 KB

english, 2001

50

Revised sequence for the lac repressor

BEYREUTHER, KONRAD

Journal:

Année:

1978

Fichier:

PDF, 102 KB

1978